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Timing: Morning injections are preferred, aligning with natural circadian fat metabolism

The proportion of phagocytosing PBMC ( Figure 5A ) increased by 47% in both groups after LPS administration until 3 h pi and then decreased to reach the baseline level at 24 h pi

Linagliptin significantly increased LS-mean insulin response to OGTT by 55% (95% CI 39.05, 71.74%) in the high GLP-1 compared to 12% (95% CI -4.05, 29.01%) in low GLP-1 group, resulted in a significant between-group difference (p = 0.002) ( Figure 3F )

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